Clinical research is a broad area of science that focuses on the development, production, and testing of both diagnostics and therapeutics meant for human use. DNA sequencing is used in a variety of related fields such as gene therapy, antibody discovery, non-invasive prenatal testing (NIPT), and liquid biopsy.
Methods used in clinical research are many and constantly evolving. Picking the right method depends on the type of sample(s) being studied and the scope of the question(s) being asked for any given project. At a population level, a genome-wide association study (GWAS) using whole-exome sequencing (WES) might look for relationships between members of a specific cohort. At a cellular level, RNAseq can be used provide greater resolution than DNA sequencing can about the function of cells through the lens of gene expression.
Beyond our standard services, we are able to customize solutions for any DNA or RNA sequencing-related workflow. Usually it’s best to start with a specific project or list of requirements, especially when dealing with work that must be performed in a CLIA or CAP laboratory environment. So if you do not see exactly what you are looking for, please tell us what that is!