Functional Analysis

Functional, Pathway and Network Analysis

Complex phenotypes reflect abnormalities in the entire biological network that links cells, tissues and organ systems. A better understanding of how genetic changes work together to influence the presentation of a complex phenotype may lead to discovery and characterization of unknown biological processes.

Functional analysis mainly refers to making sense of a given “gene list” in biological context. A “gene list” can be list of variants, transcripts, or genes with associated statistics including, but not limited to, fold change, P-value, and odds ratio etc. It ranges from functional annotation, differential gene expression, canonical pathway, and biological network analysis.

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