ATAC-seq

Transposase-Accessible Chromatin Using Sequencing (ATAC-seq)

A good alternative to ChIP-seq when beginning epigenetic studies is Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq). ATAC-seq is a common assay being utilized to survey the landscape genome-wide of chromatin assembly, understand accessibility to regions, discover transcription factor binding sites, gene regulation, and more. ATAC-seq has an advantage over other epigenomic assays as it requires a small amount of starting input. Now available on 10x Chromium.

Applications
Nucleosome mapping
Discover transcription factor
Gene regulation

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